Visualizing RAD51-mediated joint molecules: implications for recombination mechanism and the effect of sequence heterology
نویسندگان
چکیده
منابع مشابه
Visualizing RAD51-mediated joint molecules: implications for recombination mechanism and the effect of sequence heterology
The defining event in homologous recombination is the exchange of base-paired partners between a single-stranded (ss) DNA and a homologous duplex driven by recombinase proteins, such as human RAD51. To understand the mechanism of this essential genome maintenance event, we analyzed the structure of RAD51-DNA complexes representing strand exchange intermediates at nanometer resolution by scannin...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2010
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkq766